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Furthermore, these antagonists are reported to diminish palatable food preferences in rodents 12 and non-human primates 13 and to reduce binge-eating episodes in humans 14

& Bonnet, J

Loffler MC, Betz MJ, Blondin DP, Augustin R, Sharma AK, Tseng YH, et al

Koehler ( in vitro , possibly by activating cAMP expression and inhibiting the activities of the signaling kinases glycogen synthase kinase 3 and ERK1/2, thereby inducing apoptosis and inhibiting the growth and survival of colon cancer cells